INACTIVATION MODE OF SODIUM CHANNELS DEFINES THE DIFFERENT MAXIMAL FIRING RATES OF CONVENTIONAL VERSUS ATYPICAL MIDBRAIN DOPAMINE NEURONS.

Inactivation mode of sodium channels defines the different maximal firing rates of conventional versus atypical midbrain dopamine neurons.

Collections Two subpopulations of midbrain dopamine (DA) neurons are known to have different dynamic firing ranges in vitro that correspond to distinct projection targets: the originally identified conventional DA neurons project to the dorsal striatum and the lateral shell of the nucleus accumbens, whereas an atypical DA population with higher max

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Outcomes of hyperbolic tapering of antidepressants

Background: In patients attempting to discontinue their antidepressant medication, there have been no prospective studies on patterns of withdrawal as a function of the rate of antidepressant reduction during the tapering trajectory, and moderators thereof.Objective: To investigate withdrawal as a function of gradual dose reduction.Design: Prospect

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Rito, funciones y significado

El rito es un universal cultural presente en todas las culturas y en su complejidad refracta dimensiones plurales de lo suction-cup-dildos humano que le otorgan un carácter misterioso y de difícil comprensión.El rito es inseparable de momentos importantes de transición en el ciclo de la vida y se acompaña de ritmo, Aquarium Substrate danza, ca

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